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CHICAGO - Complications are rare for women undergoing fertility procedures tubes: A 12-year new US study shows most often involves medications used to stimulate the ovaries, but it indicates a problem that is rarely fatal
Ovarian more -dirangsang occurred in 154 out of every 10,000 pregnancies efforts; Another complication rate of less than 10 per 10,000 attempts. There were 58 deaths were reported during the study 2000-11. The study did not have information about their cause, and with more than 1 million pregnancies effort involved, the results are conclusive, said Dr. Jennifer Kawwass, assistant professor at Emory University and lead author.
The study is the first large-scale effort to quantify the risk for US patients undergo this treatment, said Kawwass. Tuesday results were published in the Journal of the American Medical Association.
TREATMENT STUDY
The researchers examined a federal mandate report of US fertility clinics.
fancy term for the care involved in assisted reproductive technology, this term IVF. This refers to the in vitro fertilization - mixing eggs and sperm in a laboratory dish. The resulting embryo or embryos are then transferred to the uterus. A type of IVF involves injecting a single sperm into an egg included in this study
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fertility drug that is used with IVF to stimulate the ovaries to produce eggs. high doses may cause ovarian mild swelling and abdominal bloating. severe cases may involve continuous pain, weight loss is quite large, vomiting and dangerous blood clots.
The data covers women using their own eggs and eggs donated.
MORE ON COMPLICATIONS
Death, including 18 within 12 weeks of starting fertility drugs - suggesting the drug may have played a role. 40 other deaths occurred later, showed complications related to pregnancy may have been involved; 18 of these women carrying twins, triplets or more. The report does not list the exact cause of death
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Rates for over-stimulated ovaries do not change during the study but the price for the drug side effects and hospitalizations decreased. steady rate seen for other problems, including infection, bleeding and anesthesia complications.
The most rare complication in donor, which is usually a healthy young woman, and not die.
WHAT EXPERTS SAY
Dr. Richard Paulson, vice president of the American Society for Reproductive Medicine, said a lot of complications and death could have been from the underlying condition that causes infertility, rather than treatment
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doctors in recent years have limited the number of embryos transferred, to reduce the possibility of multiple births are unsafe. Paulson, director of the University of Southern California fertility program, said the move could lead to a decline in several complications including those related to over-stimulated ovaries.
Dr. Jamie Grifo, director of the fertility center at New York University, noted that about 2 percent of US babies born from IVF, and said the study confirms that the risk faced by women undergoing a minor procedure.
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